It makes sense, if you think about it, for the decline of large firm employment to lead to more people starting their own businesses. Either they were forced to retire early, or they took a buyout, or they just could see the handwriting on the wall. For any of those reasons, and often with the help of severance checks, unemployment, or retirement benefits, more and more ex-employees are becoming entrepreneurs. They are pursuing long-term dreams, or filling needs that large firms have abandoned.
Of course, they need different types of space. That's partially why we are still seeing too much office space on the market, and why flex space, especially in small increments, in greater demand. Over time, if these new firms prosper, it may lead to new uses for the office space, or for building of more manufacturing and distribution facilities. Let's hope so!